Comparative Analysis of Bacterial Microflora Isolated from Adult Pneumonia Inpatients and Hospital Objects in the Amur Region

Background: The COVID-19 pandemic has exacerbated the problem of healthcare-associated infections and worsened situation with hospital spread antibiotic resistant strains potentially inducing nosocomial infections. Objective: To compare bacterial microflora isolated from adult pneumonia inpatients objects to assess risk hospital-acquired in Amur Region. Materials methods: study was conducted a multidisciplinary “COVID” hereinafter referred as Hospitals 1 2, respectively. Parallel bacteria culture testing 519 sputum samples 284 486 wipe collected weekly during 12 weeks both hospitals carried out using classical method. AutoSCAN-4 Vitek® 2 Compact 30 analyzers were applied identify pathogens determine their antimicrobial susceptibility. Results: Along detection pathogenic 33.8 % hospitalized patients pneumonia, we found 23.3 12.4 respectively, established that proportion Gram-negative them 44.9 15.4 while share multidrug-resistant 32.7 3.8 %. significant differences observed can be attributed more stringent disinfection regime Hospital 2. structure noted for high carbapenem-resistant organisms (20.0 %) (38.9 samples. Conclusion: Our monitoring results helped define composition ratio cases objects. A wide range pathogens, including those antibiotics, often detected accumulation over time indicate potential hazard environment posing an increased